A substance in the body that may indicate the presence of cancer. Markers may be secreted by the tumour itself or produced by the body in response to the cancer. Tumour markers may aid diagnosis or give an indicator of how treatment is progressing. These markers are usually specific to certain types of cancer. For example neuron-specific enolase (NSE) is associated with a number of types of cancers, in particular neuroblastoma. Also alphafetoprotein (AFP) levels are often abnormally high in patients with Germ cell tumours. Tumor markers are substances found at higher than normal levels in the blood, urine, or body tissue of some people with cancer. Tumor markers are also called biomarkers
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Journal of Cancer Biology and Clinical Oncology 