Margins: When a tumor is removed, it’s examined to determine if the borders of the tumor are cancer-free. If there are cancer cells on the border, more surgery may be required. The edge or border of the tissue removed in cancer surgery. The margin is described as negative or clean when the pathologist finds no cancer cells at the edge of the tissue, suggesting that all of the cancer has been removed. Margins free of cancer are considered clean, clear or negative, which is the goal of the surgery. Margins that still have cancer cells are positive and more surgery, or re-excision, may be necessary to remove them.
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