A core biopsy is a procedure where a needle is passed through the skin to take a sample of tissue from a mass or lump. The tissue is then examined under a microscope for any abnormalities. Core biopsy may be performed when a suspicious lump is found, for example a breast lump or enlarged lymph node, or if an abnormality is detected on an imaging test such as x-ray, ultrasound or mammography. Core biopsy is a more invasive procedure than fine needle aspiration biopsy, as it involves a local anaesthetic. However, it is quicker and less invasive than a surgical biopsy. In some cases, the result of a core biopsy will prevent the need for surgery to take place.
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Journal of Cancer Biology and Clinical Oncology 