Parenchyma is the bulk of a substance. In animals, a parenchyma comprises the functional parts of an organ and in plants parenchyma is the ground tissue of nonwoody structures. The parenchyma is the functional parts of an organ in the body. This is in contrast to the stroma, which refers to the structural tissue of organs, namely, the connective tissues. The brain parenchyma refers to the functional tissue in the brain that is made up of the two types of brain cell, neurons and glial cells. Damage or trauma to the brain parenchyma often results in a loss of cognitive ability or even death. Lung parenchyma is the substance of the lung outside of the circulation system that is involved with gas exchange and includes the alveoli and respiratory bronchioles. In cancer, the parenchyma refers to “The portion of a tissue that lies outside the circulatory system and is often responsible for carrying out the specialized functions of the tissue”.
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Journal of Cancer Biology and Clinical Oncology 