A proteome is the set of proteins thought to be expressed by an organism. The majority of proteomes is based on the translation of a completely sequenced genome, and will normally include sequences that derive from extra-chromosomal elements such as plasmids or organelle genomes in organisms where these occur. Some proteomes may also include protein sequences based on high quality cDNAs that cannot be mapped to the current genome assembly due to sequencing errors or gaps. The proteome of a species or an organ. The proteome is not constant; it differs from cell to cell and changes over time.

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