A substance that is made from soybeans and is being studied in the prevention of cancer. It blocks the action of enzymes that are needed for cancer cells to form. It is a type of protease inhibitor. Also called BBIC.
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A partial or complete block of the small or large intestine that keeps food, liquid, gas, and stool from moving through the intestines in a normal way. Bowel obstructions may be caused by a twist in the intestines, hernias, inflammation, scar tissue from surgery, and certain types of cancer, such as cancers of the stomach, colon, and ovary. They may also be caused by conditions that affect the muscles of the intestine, such as paralysis. Signs and symptoms may include pain and swelling in the abdomen, constipation, diarrhea, vomiting, and problems passing gas. Most bowel obstructions occur in the small intestine. Also called intestinal obstruction.
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A rare type of leukemia in which abnormal B-lymphocytes (a type of white blood cell) are present in the bone marrow, spleen, and peripheral blood. When viewed under a microscope, these cells appear to be covered with tiny hair-like projections.
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A condition in which there are no sperm in the semen when a man ejaculates. This may be because the man does not make sperm or because the sperm is blocked from entering the semen. Azoospermia may be caused by hormone problems, certain genetic conditions, previous vasectomy or other surgery, or other conditions. It may also be caused by certain cancer treatments. Azoospermia can cause infertility (the inability to produce children).
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A drug used alone or with other drugs to treat adults with multiple myeloma. It is used in patients whose cancer is newly diagnosed and who cannot be treated with an autologous stem cell transplant. Daratumumab is also used in patients whose cancer came back or did not get better after treatment with one or more anticancer therapies. It is also being studied in the treatment of other types of cancer. Daratumumab binds to a protein called CD38, which is found on some types of immune cells and cancer cells, including myeloma cells. Daratumumab may block CD38 and help the immune system kill cancer cells. It is a type of monoclonal antibody. Also called Darzalex.
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A rare, slow-growing tumor of blood vessels that forms in or under the skin anywhere on the body. Dabska tumors may appear as firm, raised, purplish bumps, which may be small or large. They usually do not spread to other parts of the body. Dabska tumors can occur in children and adults. They are a type of vascular tumor. Also called papillary intralymphatic angioendothelioma.
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A drug used to treat hepatocellular carcinoma (a type of liver cancer) that has already been treated with sorafenib. It is also used to treat advanced renal cell carcinoma (a type of kidney cancer). It is also being studied in the treatment of other types of cancer. Cabometyx blocks certain proteins, which may help keep cancer cells from growing. It may also prevent the growth of new blood vessels that tumors need to grow. Cabometyx contains the active ingredient cabozantinib-s-malate. It is a type of tyrosine kinase inhibitor and a type of angiogenesis inhibitor.
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A drug used with prednisone to treat hormone-resistant prostate cancer that has spread and that had been treated with docetaxel. It is also being studied in the treatment of other types of cancer. Cabazitaxel blocks cell growth by stopping cell division and may kill cancer cells. It is a type of antimitotic agent. Also called Jevtana and taxoid XRP6258.
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A benign (not cancer) condition in which there are more cells than normal in the lining of breast ducts and the cells look abnormal under a microscope. Having atypical ductal hyperplasia increases the risk of breast cancer. Also called ADH and atypical ductal breast hyperplasia.
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A drug used to lower the amount of cholesterol in the blood and to prevent stroke, heart attack, and angina (chest pain). It is also being studied in the prevention and treatment of some types of cancer and other conditions. Atorvastatin calcium blocks an enzyme that helps make cholesterol in the body. It also causes an increase in the breakdown of cholesterol. It is a type of HMG-CoA reductase inhibitor and a type of statin. Also called Lipitor.
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Journal of Cancer Biology and Clinical Oncology 